Stephen G. Lomber, Scientist; Canada Research Chair in Brain Plasticity and Development; Professor, Departments of Physiology & Pharmacology and Psychology
Our laboratory uses an integrated approach of psychophysics, electrophysiological recording, neuroanatomical approaches, and functional imaging to examine multisensory processing in the auditory cortex. The lab pioneered the use of focal cooling to reversibly deactivate regions of the cerebrum. Work in the lab examines cortical plasticity in the presence and absence of acoustic input, and following the initiation of auditory processing through the use of cochlear prosthetics.
How does experience influence brain development and influence adaptive neuroplasticity?
In order to answer this question we are presently pursuing three different avenues of investigation:
- Cortical Processing and Organization in the Hearing Subject
- Cortical Processing and Organization in the Congenitally Deaf
- Cortical Processing and Organization in the Deaf Following Cochlear Implant
Ph.D. Boston University School of Medicine
B.Sc. University of Rochester
Fellow of the Association for Psychological Science
Funded by the Canadian Institutes of Health Research (CIHR), Natural Sciences and Engineering Research Council of Canada (NSERC), Canada Foundation for Innovation (CFI) and The Hearing Foundation of Canada.
Authored more than 125 research publications and has edited two books, Virtual Lesions with Ralf Galuske and Reprogramming the Cerebral Cortex with Jos Eggermont. And presently editing The Oxford Handbook of Cortical Plasticity.
Lomber, S.G., Meredith, M.A. and Kral, A. (2010) Crossmodal plasticity in specific auditory cortices underlies visual compensations in the deaf. Nature Neuroscience 13: 1421-1427.
Meredith, M.A., Kryklywy, J., McMillan, A.J., Malhotra, S., Lum-Tai, R. and Lomber, S.G. (2011) Crossmodal reorganization in the early-deaf switches sensory, but not behavioral roles of auditory cortex. Proceedings of the National Academy of Sciences (USA) 108: 8856-8861.
Butler, B.E. and Lomber, S.G. (2013) Functional and structural changes throughout the auditory system following congenital and early-onset deafness: implications for hearing restoration. Frontiers in Systems Neuroscience 7:92. pgs. 1-17.
Wong, C., Chabot, N., Kok, M.A., and Lomber, S.G. (2014) Modified areal cartography in auditory cortex following early and late-onset deafness. Cerebral Cortex 24: 1778-1792.
Hall, A.J. and Lomber, S.G. (2015) High-field fMRI reveals tonotopically-organized and core auditory cortex in the cat. Hearing Research 325: 1-11. PMID: 25776742.
Kral, A. and Lomber, S.G. (2015) Deaf white cats. Current Biology 25: R351-353.
Social Science Centre, Rm. 9232
Phone: 519.663-5777 ext. 24110